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Cell Research reports “Increased IL-1β activation, the culprit not only for defective insulin secretion but also for insulin resistance?”

Posted on October 25, 2020October 26, 2020 by vaccinereport

Regardless of the precise underlying mechanism, an impressive number of genetic animal models now demonstrate a role for the inflammasome in mediating IL-1β-induced insulin resistance. This is further supported by earlier intervention studies showing that IL-1 blockade in animal models of diabetes improved both insulin secretion and sensitivity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193499/

Autoimmunity Diabetes Medicine Research
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